Creatinine is a by-product of creatine, a component of muscle. Physicians check creatinine levels to determine how the kidney's are functioning. If creatinine is high, it ways the kidneys are non operation properly.

Certain drugs can also cause creatinine levels to rise.

Chemotherapy Drugs

IV with hospital patient

Several chemotherapy drugs like Cisplatin, Carbplatin, Carmustine, Mitomycin and Methotrexate may cause kidney damage and produce elevated creatinine levels. Patients receiving these drugs must have labs drawn prior to administration to check their creatinine levels to make sure that their kidneys can handle the drugs.

Antibiotics

Senior woman holding two pills, close-up of hand

Antibiotics such as Amphotercin B, Gentamycin and Vancomycin can also cause damage to the kidneys and raise creatinine levels.

Angiotensin Converting Enzyme Inhibitors (ACE)

Man with chest pain

ACE inhibitors are typically given to patients after middle attacks considering they overstate the claret vessels of the center and lower blood force per unit area. Some patients with dumb kidney role, such as narrowing of the arterial vessels in the kidneys, should not take ACE Inhibitors because they tin can farther harm the kidneys and heighten creatinine levels.

NSAIDS (nonsteroidal anti-inflammatory Drugs)

Bottle of aspirin lying on its side, tablets spilling out

Pain relievers such as motrin (ibuprofen), aspirin, and naproxen can crusade side effects such as kidney failure. Because of this side effect they are listed a possible causes of increased creatinine levels.

Diuretics

Public toilet, elevated view

Diuretics such as furosemide (Lasix) tin cause creatinine levels to increase. According to an article on medscape.com, long-term use of diuretics can crusade the kidney'due south to work overtime trying to compensate and the outcome is an increase in sodium resorption which can farther lead to elevated creatinine levels.

References

Writer Bio

Rebecca McClinton has been freelance writing since 2003. She currently works in a hospital pharmacy and maintains a hospital-wide spider web page for over 75 hospital administrative administration. She received a degree in English from the University of New Hampshire. Due to her work at the hospital, she has experience in joint commission infirmary accreditation practices.

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